Alzheimer’s disease is a progressive neurodegenerative disease with clinical manifestations of progressive dementia, memory loss and cognitive decline.
The causes of Alzheimer's disease
Currently, the exact pathogenesis of Alzheimer’s disease is still unclear. Recent studies show that protein precipitation is the leading cause of Alzheimer’s disease. Abnormal accumulation of proteins forms β-amyloid plaques and bundles in the brain, which ultimately leads to a decrease in connective nodes in the brain, which is mainly associated with a decrease in cognitive abilities.
Harmful accumulation of the protein
In addition to beta-amyloid in the nerve cells of patients with Alzheimer’s disease, there are some other harmful proteins that come together to form globular fibers that destroy the normal function of nerve cells. This protein is a component of microtubules that are separated from a transport tube that transports nutrients so that the derivatives of nerve cells die without power.
Traditional treatment of Alzheimer's disease
Alzheimer’s disease is still not cured, doctors can only use a small amount of medication to relieve the patient’s symptoms. Currently, cholinesterase inhibitors such as donepezil are the primary treatment for Alzheimer’s disease. The main effect is to delay the deterioration of neuronal function and has a certain effect in the early stages of Alzheimer’s disease. Since the onset of Alzheimer’s disease is more insidious and less noticeable, most patients begin to take the drug at the middle and late stages of the disease, so the effect of treatment is not satisfactory.
In addition to treatment, home care, can reduce the patient’s loneliness and make sure that he can remember some things to achieve a stable mood. However, with further increase in the age of the patient and resistance of patients to the drugs worsen the function of neurons and the symptoms of dementia become more apparent, which will bring huge burden to the family.
Clinically detailed and scientific care plays a crucial role in the correction of the patient’s behavior and the recovery of memory. For those who stay in bed for a long time, pay attention to regular airing and wiping to prevent bedsores. Excited patients should be accompanied by family members to avoid accidents. Pay attention to the patient’s diet and do not help, do not feed a person who can eat himself. At the same time, strengthen the training of mental abilities and memory of patients.
Stem cells and Alzheimer's disease
Alzheimer’s disease is incurable so far, doctors can only use a small amount of drugs to relieve the patient’s condition, but only have a certain effect on early patients. In recent years, the development of regenerative medicine technology based on stem cells has brought new hopes for improving Alzheimer’s disease.
Stem cells can promote the proliferation, differentiation, migration and maturation of endogenous nerve stem cells, generate new neurons and glial cells, repair damaged brain tissue, and improve neurological function.
Stem cells can contribute to local angiogenesis in traumatic brain injury, improve cerebral blood flow, restore blood supply to the brain and improve the course of the disease.
Promotes the synthesis of neurotrophic factors, regulates inflammation, promotes angiogenesis and improves survival